Drug eluting stent PPT

Drug eluting stent - SlideShar

Paclitaxel-coated balloon versus drug-eluting stent during PCI of small coronary vessels, a prospective randomized clinical trial Cortese B et al. Heart 2010;96:1291-1296 Paclitaxel-coated balloon DIOR® vs. Taxus DES in small coronary vessels (≤ 2.75 mm), n=28 + 29 patients been specifically designed for use in drug-eluting stent systems and has the highest lipophilic profile of the common limus drugs, enabling rapid absorption by the tissue and minimizing systemic exposure. The latest version of BioMatrix, the BioMatrix Flex™, launched in 2010, features a more flexible stent platform for improved deliverability

PPT - Drug Eluting Stents PowerPoint presentation free

In patients with stable ischemic heart disease (SIHD) treated with DAPT after drug-eluting stent (DES) implantation, P2Y 12 inhibitor therapy with clopidogrel should be given for at least 6 months (Class I). In patients with SIHD treated with DAPT after bare-metal stent. A stent is a small mesh tube inserted into an artery to keep it open. A drug-eluting stent is coated with a slow-release medication to help prevent blood clots from forming in a stent. Blood clotting in a stent can cause a future blockage (restenosis) and may lead to a heart attack. Stents without a drug coating are called bare-metal stents Drug eluting stents (DES) have turned up as a potential solution for restenosis. DES are combination products composed of a medicinal product(s) and medical devices and since the medicinal product(s) has an ancillary function to the device they are in accordance with the Council Directive 93/42/EE Third-generation drug-eluting stents and beyond: Where were we, where are we, and where we are heading. 27th June 2018. 9558. Michael Maeng. Second-generation drug-eluting stents resolved the issues of late and very late stent thrombosis that were seen with the first-generation devices and have good safety and efficacy data Physicians talk about the importance of drug-eluting stents in complex lesions and how the Eluvia Drug-Eluting Stent is designed to deliver controlled, localized, low-dose amorphous paclitaxel to target lesions. See how over a decade of research helped Eluvia engineers develop the first drug-eluting stent for the SFA designed to sustain drug.

PPT - Drug Eluting Versus Bare Metal Stents PowerPoint

stents (BMS) decrease d acute recoil and arterial shrinkage caused by balloon angio plasty. However, ne ointimal hyper-plasia leading to in-stent restenosis af ter BMS implantation h as been emerged a new obsta cle. Recent introduction of drug-eluting stents (DES) contributes a powe rful breakthrough to PCI A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (), could otherwise block the stented artery, a process called restenosis.The stent is usually placed within the peripheral or coronary artery by an. Initially, drug-eluting stents (DES) were compared to bare-metal stents (BMS) for efficacy. The first double-blind randomized study was the RAVEL trial, [] which compared the sirolimus-eluting CYPHER stent with its noncoated counterpart, the BX velocity stent, in 238 patients with de novo lesions less than 18 mm in length in native coronary arteries 2.5-3.5 mm in diameter

Orsiro's safety and efficacy The ultrathin Orsiro drug-eluting stent (DES), launched in the CE-market in 2011 and approved by the FDA in 2019, is a unique so.. Objective To compare the efficacy and safety of biodegradable polymer drug eluting stents with those of bare metal stents and durable polymer drug eluting stents. Design Mixed treatment comparison meta-analysis of 258 544 patient years of follow-up from randomized trials. Data sources and study selection PubMed, Embase, and Central were searched for randomized trials comparing any of the Food. Percutaneous coronary intervention (PCI) is 40 years old this year. From its humble beginnings of experimental work, PCI has transitioned over years with coronary artery stenting now a standard medical procedure performed throughout the world. Areas covered: The conversion from plain old balloon ang The makers of drug-eluting stents have agreed that compared with bare-metal stents there is a small, but significant increase in the rate of stent thrombosis for both the Cypher (sirolimus-eluting) and Taxus (paclitaxel-eluting) stents, beginning about 12 months after implantation. But they are at a loss to explain the increase Author: Stephan Windecker, Onyx ONE -A Randomized Trial of a Durable-Polymer Drug-Eluting Stent vs. a Polymer-Free Drug-Coated Stent in Patients at High Risk of Bleeding Treated With 1-Month DAP

Drug-eluting stents are placed in a fashion similar to other stents; however, their use markedly reduces the rate of renarrowing. In fact, about 1 in 10 patients develops renarrowing in the several years after drug-eluting stent implantation, a rate about half of that seen for stents without medication Byrne RA, Kastrati A, Massberg S, et al. Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial. J Am Coll Cardiol 2011; 58:1325 Delayed arterial healing and increased late stent thrombosis at culprit sites after drug-eluting stent placement for acute myocardial infarction patients: an autopsy study. Circulation. 2008; 118:1138-1145. Link Google Scholar; 4. Virmani R, Farb A, Guagliumi G, Kolodgie FD. Drug-eluting stents: caution and concerns for long-term outcome Conclusions. Dual antiplatelet therapy beyond 1 year after placement of a drug-eluting stent, as compared with aspirin therapy alone, significantly reduced the risks of stent thrombosis and major. Intravascular ultrasound-guided vs angiography-guided drug-eluting stent implantation in complex coronary lesions: Meta-analysis of randomized trials Am Heart J. 2017 Mar;185:26-34. doi: 10.1016/j.ahj.2016.10.008. Epub 2016 Nov 12. Authors Chirag Bavishi 1.

Drug Eluting Stents (DES) - SlideShar

  1. Evaluate the safety and effectiveness of the Promus PtCr EES Coronary Stent System* for the treatment of patients with up to 2 de novo lesions ≤ 24 mm in length; ≥ 2.50 mm to ≤ 4.25 mm in diameter compared to the Xience CoCr EES. Study Design Prospective, Randomized, Controlled, Non-inferiority, Multicente
  2. INTRODUCTION. Most commercially available drug-eluting intracoronary stents (DES) consist of a metallic scaffold, a polymer coating (which may be durable or bioresorbable), and an antirestenotic drug that is mixed within the polymer and released over a period of weeks to months after implantation ().The use of current-generation DES is associated with low rates of restenosis, target lesion.
  3. drug eluting stent - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. drug eluting stent
  4. for drug-eluting stents that are aimed at improving safety and efficacy have been developed. Drug-eluting stents are now implanted in more than 500,000 patients every year in the United States.15 This review provides an overview of currently avail-able devices, summarizes evidence from randomized trials, and outlines clinical indications for use
  5. Bare Metal and 1st Generation Drug-Eluting Stents: Devices, Indications, and Presenter: Emmanouil S. Brilakis November 1, 2016. Presentation Fellows 2012
  6. The recent introduction of drug-eluting stents (DES) contributes a major breakthrough to interventional cardiology. Many large randomized clinical trials using DES have shown a remarkable.
  7. Drug-eluting stents deliver potent compounds directly to arterial segments but can become clot laden when deployed. The question arises as to whether thrombi affect drug elution and arterial.

Coronary artery stenting is the treatment of choice for patients requiring coronary angioplasty. Stents, and particularly drug-eluting stents, reduce the risk of restenosis, but may be associated with the hazard of late stent thrombosis. Dual anti-platelet treatment is recommended for patients receiving coronary stents Sono-Tek stent coating machines are considered the industry standard and are used by most of the largest DES manufacturers in the world. Our ultrasonic coating systems have been used to spray anti-restenosis drug eluting polymer solutions onto implantable stents for decades 4. First-generation drug eluting stents4.1. Sirolimus eluting stents. Sirolimus (Rapamycin), an immunosuppressive agent/drug with anti-migratory and anti-proliferative effects on vascular smooth muscle cells has been used to prevent rejection in organ transplantation and was the first drug to be used in the first-ever US FDA approved drug eluting Cypher stent in April 2003

The use of new stents should be restricted to 5. Ong ATL, McFadden EP, Regar E, De Jaegere PPT, Van Domburg RT, Serruys PW. Late angiographic stent thrombosis (LAST) events those with significant residual stenosis after balloon dilata- with drug eluting stents Drug-eluting stents (DES) are predominantly used in coro-nary angioplasty procedures for reducing in-stent restenosis. Their distinguished therapeutic effect is attributed to the prolonged local release of anti-inflammatory or antiprolifer-ative drugs from a polymeric stent coating into the arteria Two types of stents are available for use, a stent that is coated with a drug intended to reduce the risk of future blockages (drug-eluting stent) and an uncoated stent (bare-metal stent). In this review, we aimed to assess the benefits and harms of drug-eluting stents compared with bare-metal stents drug eluting stents (DES) were developed. 3 II-2 Legal basis Coronary stents fall within the scope of the MDD. In DES, the medicinal substance(s) incorporated in the stent has/have an ancillary action to that of the stent within in the meaning of Article 1.4 of the MDD. In view of the above and pursuant to Article 9 of the MDD, the applicabl Onyx ONE: A Randomized Trial of a Durable-Polymer Drug-Eluting Stent vs. a Polymer-Free Drug-Coated Stent in Patients at High Risk of Bleeding Treated With 1-Month DAPT Presenter: Stephan Windecker September 26, 201

PPT - Drug Eluting VS Bare Metal Stents PowerPoint

  1. Patient-level data from 10 randomized trials comparing DCB angioplasty to repeat drug-eluting stent (DES) implantation in the treatment of coronary ISR (710 patients with BMS [bare-metal stent]-ISR and 1,248 with DES-ISR) were included in this analysis. The primary efficacy endpoint was target lesion revascularization (TLR) at 3 years
  2. Indeed, the recent achievements in stent technologies, with thinner struts, absent or bioresorbable polymer, and sharper imaging-assisted implantation techniques, have further improved clinical outcome with drug-eluting stents (DES), with reduced rates of restenosis and thrombotic complications, allowing a shorter DAPT duration (even as short.
  3. The aim of the PICCOLETO II (Drug Eluting Balloon Efficacy for Small Coronary Vessel Disease Treatment) study by Bernardo Cortese, San Carlo Clinic, Milano, Italy, and colleagues was to compare the performance of a novel drug-coated balloon (Elutax SV, Aachen Resonance, Germany), with an everolimus-eluting stent (Abbott Vascular, Santa Clara.
  4. Background Acute myocardial infarction (AMI) complicates the clinical management of atrial fibrillation (AF) because coronary stenting may influence subsequent antithrombotic therapy. We investigated the use of a bare-metal stent (BMS) or a drug-eluting stent (DES) and associated outcomes in patients with pre-existing AF and first AMI undergoing percutaneous coronary intervention
  5. View Transcript Download Transcript. In this video, Dr Upul Wickramarachchi (Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK) discusses the clinical outcomes of drug-coated balloon angioplasty treated patients versus drug-eluting stent treated patients for de novo coronary artery disease in all vessel sizes

In-stent restenosis (ISR) has been a major drawback with percutaneous coronary intervention (PCI). Intervention of ISR lesions constituted 20% to 40% of all PCIs in the era of bare metal stents (BMS) .Although drug-eluting stents (DES) substantially reduced the rates of ISR compared with BMS, the expansion of indications for PCI to complex coronary lesions in high-risk patients still makes ISR. August 27, 2012 -- Three year results from the largest randomized clinical trial of drug-eluting stents ever conducted, and the only trial sufficiently powered to measure stent thrombosis, show low rates of blood clots occurring inside drug-eluting stents implanted in real-world patients. Presented this morning in Munich by Dr. William Wijns at the 2012 Annual Meeting of the European Society. savings associated with funding of Zilver paclitaxel drug-eluting stents would be $470,000 to $640,000 per year, assuming that the use of the Zilver paclitaxel drug-eluting stent was associated with a lower risk of subsequent revascularization. Conclusions Based on evidence of low to moderate quality, Zilver paclitaxel drug-eluting stents wer Percutaneous coronary intervention with implantation of drug-eluting stents (DES) has reduced the need for repeat revascularisation compared with bare-metal stents (BMS).1 However, first-generation DES with durable polymers were associated with a slightly increased risk of stent thrombosis, especially very late stent thrombosis after discontinuation of dual antiplatelet therapy.2,3 New.

PPT - Hidden Menace -Stent Thrombosis in Drug Eluting

Unanswered Questions — Drug-Eluting Stents and the Risk of Late Thrombosis By the end of 2004, drug-eluting stents were used in nearly 80% of percutaneous coronary interventions in the United. September 22, 2016—Stefan Müller-Hülsbeck, MD, presented 24-month results from the MAJESTIC trial of Boston Scientific's Eluvia drug-eluting vascular stent system during the Super Tuesday session on September 13 at CIRSE 2016, the annual meeting of the Cardiovascular and Interventional Radiology Society of Europe, held in Barcelona, Spain

Hofma SH, Ong ATL, Aoki J, van Mieghem CAG, Rodriguez Granillo GA, Valgimigli M, Regar E, de Jaegere PPT, McFadden EP, Sianos G, et al. One year clinical follow up of paclitaxel eluting stents for acute myocardial infarction compared with sirolimus eluting stents. Heart. 2005 Sep; 91 (9):1176-1180. [PMC free article Introduction. Percutaneous coronary intervention with bare-metal stents (BMS) or drug-eluting stents (DES) has become one of the most frequently performed therapeutic procedures for coronary artery disease.1 The rate of in-stent restenosis (ISR) in clinical practice is nearly 5% of patients treated with DES and 10% with BMS after 5 years.2 Given the number of patients undergoing a stent. Introduction. Dual antiplatelet therapy (DAPT), with aspirin and a P2Y 12-receptor inhibitor, is a basis for the care of patients after percutaneous coronary intervention (PCI).1 2 3 The recommended duration of DAPT for patients after drug-eluting stent (DES) implantation is ≥12 months for patients with acute coronary syndrome (ACS), and six months for patients with stable coronary artery. Late angiographic stent thrombosis (LAST) events with drug-eluting stents. Program and abstracts from the European Society of Cardiology Congress 2005; September 3-7, 2005, Stockholm, Sweden. Introduction Coronary bifurcation lesions (CBL) constitute a fifth of all coronary lesions and have no optimal method for treatment.(1) Multiple trials were conducted to investigate different modalities of treatment such as drug eluting stents, bioresorbable scaffolds, and dedicated bifurcation stents.(2) There are limited data discussing the clinical outcomes of these trials as most tend to.

Harvard Business Case Studies Solutions - Assignment Help. Drug Eluting Stents: A Paradigm Shift in the Medical Device Industry is a Harvard Business (HBR) Case Study on Strategy & Execution , Fern Fort University provides HBR case study assignment help for just $11. Our case solution is based on Case Study Method expertise & our global insights.. Patients who underwent percutaneous coronary intervention with a drug-eluting stent and maintained dual antiplatelet therapy without any clinical events within 6-18 months after the index procedure were eligible for this study and underwent randomisation. The primary efficacy endpoint was analysed during the 24-month follow-up duration in the. The new product under consideration here is the drug-eluting stent: a device which props open a clogged artery to the heart and then releases medication that reduces the risk of artery re-blockage. In light of recent medical and competitive trends in the market, the case prompts students to examine the future adoption of drug-eluting stents as. Interv Cardiol. 2012;4(1):1557-1564. Although drug-eluting stents (DES) are more effective than bare-metal stent (BMS) in reducing restenosis rate, there is the need for a prolonged dual. The MarketWatch News Department was not involved in the creation of this content. Jul 18, 2021 (CDN Newswire via Comtex) -- The new report entitled Global Next-Generation Drug-Eluting Stent Market.

Drug Eluting Stents and Bare Metal Stents PDF

  1. al bioabsorbable polymer coating available in the U.S. It was designed to address the challenges associated with permanent polymer stents such as inflammation, neoatherosclerosis and late stent thrombosis. The SYNERGY BP Stent provides synchronous drug elution and.
  2. Percutaneous coronary intervention and drug-eluting stent use among patients ≥85 years of age in the United States. Perioperative Management of Dual-Antiplatelet Therapy in Patients With New-Generation Drug-Eluting Metallic Stents and Bioresorbable Vascular Scaffolds Undergoing Elective Noncardiac Surgery
  3. BACKGROUND: Polymers components of early-generation drug-eluting stents have been implicated in the pathogenesis of delayed arterial healing, vessel remodeling, and delayed stent thrombosis. Recently, a novel polymer-free BES has shown excellent clinical performance in clinical trial setting
  4. The FDA has approved Medtronic's Resolute Onyx drug-eluting stent, which the company has now launched in the USA. As stent technologies continue to evolve, recent clinical studies have shown that newer technologies have not established a clinical advantage over durable polymer drug-eluting stent, says Roxana Mehran, cardiologist and professor of medicine at Mount Sinai School [

Drug-eluting stent - Cardiology PowerPoint Presentation

Bare metal stent vs drug eluting stent PPT — drug eluting

PPT - Is There Still a Controversy About Stent Type forPPT - Current Status of DRUG ELUTING BALLOONS FOR SFA/POP

1985 - Palmaz Stent 1986 - first intracoronary stent 1994 -FDA approval 2003 -First drug eluting stent. Peripheral Interventions. Renal Intervention. Catheter Based Therapeutics. Stations in The Cardiac Catheterization talk.ppt Author: Microsoft Corporation Created Date Drug-Eluting Stents 1. Stent thrombosis 2. Stent fractures Pre-PCI Post-PCI 6 months post-PCI 3. Coronary aneurysms 4. Bleeding complications from prolonged DAPT 5. Risks of going for surgery while on 1 year of DAPT 6. Loss of normal vasomotor function of coronary artery 7. Cost (Average $3000/stent

Drug-eluting Stent A stent is a spring-like device that is temperature sensitive. Compressed and supercooled, it is inserted into an artery, routed through the body and deployed at the point of an aneurysm, at which time it expands to its desired diameter and supports the walls of the artery. ____ Initial studies of drug-eluting stents (DES) in the SFA were hampered by lack of clinical benefit compared to non-DES. These early DES included both sirolimus-eluting and everolimus-eluting designs using an earlier-generation stent platform.11,12 Subsequently, a paclitaxel-eluting stent has shown significant benefit in the SF alloy stents were the mainstay of PCI. The introduction of drug eluting stents (DES) targeted in-stent restenosis, a common mode of stent failure, and ushered in the current PCI era. Since the first generation of DES, advances in polymer science and stent design have advanced the field Search all fields; Search by keyword; Search by author; Search by journal; Search by institution; Search by article; Advanced searc

ACC/AHA Guideline Update on Duration of Dual Antiplatelet

Drug-eluting stents: Do they increase heart attack risk

Stefanini GG, Byrne RA, Serruys PW, et al. Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomized trials. Eur Heart J 2012; 33:1214 Drug-eluting stents were consistently associated with a higher incidence of repeat revascularization, whereas coronary artery bypass grafting had a higher incidence of stroke. The incidence of major adverse cardiac and cerebrovascular events was similar between the 2 groups at 30 days but higher for drug-eluting stents at 12 months and beyond Decreased estimated glomerular filtration rate (eGFR) is a strong predictor of both mortality and subsequent cardiac events after percutaneous coronary intervention. The safety and efficacy of drug-eluting (DESs) versus bare-metal stents (BMSs) in this population have not been evaluated adequately PURPOSE: Long term safety of drug eluting stents (DES) is controversial. There is growing concern regarding late stent thrombosis, and associated myocardial infarction and mortality with DES. The objective of the study was to determine the long term outcome of DES and its comparison with bare metal stents (BMS)

Drug Eluting Stents - DES Market Report 2021,Abbott Vascular, Advantec Vascular, B.Braun Melsengen AG, Biosensors, Biotronik, Blue Medical Sahajanand, Sino Medical, Sorin, Terumo Medical,Coronary Heart Disease, Clinical,Cobalt chromium alloy Stents, Magnesium alloy Stents, Tyrosine polycarbonate Stents, Nitinol Stents, Platinum chromium. Medtronic's Resolute Onyx Drug Eluting Stent with CoreWire Technology. November 3rd, 2014 Medgadget Editors Cardiology, Radiology. Medtronic received CE Mark approval and is launching the Resolute. In the subgroup treated by newer generation drug-eluting stents, MACE was 12.0% vs 5.6% (HR 0.45, 95% CI 0.17 to 1.17, p=0.10) after simple versus complex treatment. Conclusion In the treatment of bifurcation lesions involving a large SB with ostial stenosis, routine two-stent techniques did not improve outcome significantly compared with.

Third-generation drug-eluting stents and beyond

Drug-eluting balloon for in-stent restenosis Yin Chen, Shilian Hu, Lei Wu To the Editor: We read with interest the meta-analysis by Indermuehle A et al which reported that drug-eluting balloon (DEB) appears to show great promise for in-stent restenosis (ISR), and could reduce the risk for major adverse cardiac events (MACE) compared with plain. Drug eluting stent is expected to lead the market during the forecast period due to innovations and technological advancement in stent technology. Bioresorbable stent is predicted to exhibit the highest growth rate during the forecast period owing to surging adoption among healthcare professionals and patients due to its characteristics, such. Coding New Technology: Challenges and Opportunities ICD-9-CM Coordination and Maintenance Committee November 1-2, 2001 John D. Shaw, President Dilemma: Irresistible Force Meets Immovable Object Irresistible Force of New Technology Rapid Development - Min. Invasive, Bio-tech 5 Year Patient Wait After FDA is Unacceptable Congress Linked Payment to New ICD-9 codes Immovable Object of ICD-9-CM. Drug-eluting stents, bare-metal stents, and self-expanding stents. Stone et al, examining the safety and efficacy of drug-eluting and bare-metal stents in 3006 patients with STEMI undergoing primary PCI, found that the drug-eluting stents, as compared with bare-metal stents,.

Introduction of drug eluting stents (DES) reduced this problem dramatically (1,2). Recently, studies have indicated that this reduction in restenosis might have been obtained at the expense of a higher incidence of stent thrombosis, particularly late stent thrombosis. This supposition has reignited a debate about the mechanisms of stent. Το perform a systematic review and meta-analysis of the available literature comparing safety and efficacy outcomes between percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and coronary artery bypass grafting (CABG) in patients with chronic kidney disease (CKD). Eligible studies included patients with eGFR < 60 mL/min/1.73 m2 that underwent revascularization

Ascending thoracic aorta stent graft - Hercules™-T

Eluvia™ Drug-Eluting Vascular Stent System - Boston Scientifi

A decade ago, balloon angioplasty was the mainstay of treatment, currently, bare-metal stents, drug-eluting stents (DESs), atherectomy devices, and cryoplasty have been explored with varying degrees of success. Over the past few years, DESs in the infrapopliteal vessels have shown promising results Non biodegradable Polymer based Drug Eluting Stent Market Report 2021,Boston Scientific Corporation, Medtronic, Lepu Medical, Stentsys,Coronary Artery Disease, Peripheral Artery Disease,Micro porous Surface, Slotted Tubular Surfac However, after clopidogrel discontinuation patients receiving drug-eluting vs bare-metal stents experienced higher rates of death and MI (4.9% vs 1.3%, respectively). These results have created uncertainty regarding the minimal necessary duration of antiplatelet therapy after drug-eluting stent implantation The introduction and widespread adoption of drug-eluting stents into routine clinical practice has seen tremendous changes in the practice of interventional cardiology. For a prolonged period, manufacturers have focused research on drugs and polymers that are the key to the prevention of in-stent restenosis. However, stent platform design and. Drug eluting peripheral stents provide efficacy and safety, improved long term outcomes and reduction in the stent thrombosis. Drug eluting peripheral stents is primarily driven by the elevating a number of graying population as they are a high risk of developing artery disorders

Drug-eluting stent - Wikipedi

Stent thrombosis is an infrequent (1-2%) but serious complication of stent placement. It occurs most commonly within the first month, but rarely can occur as late as 1 year (0.2-0.6%) with bare metal stents. Very late stent thrombosis (VLST), which occurs after 1 year, is very rare with bare metal stents but can occur with drug-eluting stents LEADERS FREE II: evaluation of a polymer-free coronary drug-eluting stent in high bleeding-risk patients with one-month DAPT Reported from TCT 2018 in San Diego LEADERS FREE II was designed to demonstrate the reproducibility of the initial results of the first LEADERS FREE trial and to support a potential FDA registration for the BioFreedom.

Coronary Drug-Eluting Stent: Products, Design Features

Stent thrombosis is one of the most feared complications of percutaneous coronary intervention. Most commonly it occurs within the first few days after the deployment of the stent. Once the stent is completely endothelialized, this complication becomes extremely rare. Few cases of very late stent thrombosis were reported in the literature with the longest interval being around 11 years after. Editor—We read with interest the report1 of 'bridging' antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel, in the presence of drug-eluting stents (DES), for non-cardiac surgery and noted the similarity of this group's regimen to that already described in this journal in 2007 by our group.2 The rationale for including unfractionated heparin in our bridging.

PPT - Renal Artery Stenosis PowerPoint Presentation - IDCoracto Istanbul 2011